NMDA antagonist MK801 recreates auditory electrophysiology disruption present in autism and other neurodevelopmental disorders
نویسندگان
چکیده
منابع مشابه
Toward Effective Probiotics for Autism and Other Neurodevelopmental Disorders
Hsaio and colleagues link gut microbes to autism spectrum disorders (ASD) in a mouse model. They show that ASD symptoms are triggered by compositional and structural shifts of microbes and associated metabolites, but symptoms are relieved by a Bacteroides fragilis probiotic. Thus probiotics may provide therapeutic strategies for neurodevelopmental disorders.
متن کاملAdaptation of the "ten questions" to screen for autism and other neurodevelopmental disorders in Uganda.
Neurodevelopmental disorders are recognized to be relatively common in developing countries but little data exist for planning effective prevention and intervention strategies. In particular, data on autism spectrum disorders are lacking. For application in Uganda, we developed a 23-question screener (23Q) that includes the Ten Questions screener and additional questions on autism spectrum diso...
متن کاملMaternal metabolic conditions and risk for autism and other neurodevelopmental disorders.
OBJECTIVE We examined whether metabolic conditions (MCs) during pregnancy (diabetes, hypertension, and obesity) are associated with autism spectrum disorder (ASD), developmental delays (DD), or impairments in specific domains of development in the offspring. METHODS Children aged 2 to 5 years (517 ASD, 172 DD, and 315 controls) were enrolled in the CHARGE (Childhood Autism Risks from Genetics...
متن کاملAuditory discrimination and auditory sensory behaviours in autism spectrum disorders.
It has been hypothesised that auditory processing may be enhanced in autism spectrum disorders (ASD). We tested auditory discrimination ability in 72 adolescents with ASD (39 childhood autism; 33 other ASD) and 57 IQ and age-matched controls, assessing their capacity for successful discrimination of the frequency, intensity and duration differences in pairs of sounds. At the group level, audito...
متن کاملConceptualising compensation in neurodevelopmental disorders: Reflections from autism spectrum disorder
Within research into neurodevelopmental disorders, little is known about the mechanisms underpinning changes in symptom severity across development. When the behavioural presentation of a condition improves/symptoms lessen, this may be because core underlying atypicalities in cognition/neural function have ameliorated. An alternative possibility is 'compensation'; that the behavioural presentat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Behavioural Brain Research
سال: 2012
ISSN: 0166-4328
DOI: 10.1016/j.bbr.2012.06.032